In Vitro Enzyme Activity Assay

Kinases play extensive and important roles in signal transduction and co-ordination of complex functions. Currently, about 300 kinase inhibitors have been approved for marketing, among which receptor tyrosine kinase (RTK) inhibitors are the main ones. Medicilon provides high-quality kinase profile screening and has one-stop kinase research services from assay development, high-throughput screening to selectivity analysis. In addition, Medicilon provides many other enzyme activity screens.

Wide Variety

Provides 200+ in vitro enzymatic detection methods;

100+ kinases, including CTK, RTK, AGC, CMGC and other kinase families as well as important common mutations

Project Flexibility

Various types of plates for screening, such as 96 and 384;

Multiple flexible kinase profiles, including TK kinase family, CDK kinase family, etc., to meet different customer customization needs.

Various Methods

Fluorescence detection;

Chemiluminescence detection;

Absorbance detection

LanthaScreen/AlphaScreen;

Z‘-LYTE,HTRFTR-FRET/FP;

Kinase-Glo;

ADP-Glo kinase assay, etc.

Fast Delivery

Provides compounds to be tested, 2-5 mg each, Medicilon will arrange corresponding screening and detection services, and finally provide a professional analysis report;

Screening cycle: 1-2 weeks, reporting cycle: 1-3 working days (the specific time depends on the experimental content).